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Tumor growth suppression by implantation of an anti-CD25 antibody-immobilized material near the tumor via regulatory T cell capture

In this study, we designed and synthesized an implantable anti-CD25 antibody-immobilized polyethylene (CD25-PE) mesh to suppress tumor growth by removing regulatory T cells (Tregs). The PE mesh was graft-polymerized with poly(acrylic acid), and the anti-mouse CD25 antibody was then immobilized using...

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Detalles Bibliográficos
Autores principales: Kimura, Tsuyoshi, Tokunaga, Rino, Hashimoto, Yoshihide, Nakamura, Naoko, Kishida, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344258/
https://www.ncbi.nlm.nih.gov/pubmed/34377087
http://dx.doi.org/10.1080/14686996.2021.1944782