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RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

Lipid droplets (LDs) are dynamic organelles that undergo dynamic changes in response to changing cellular conditions. During nutrient depletion, LD numbers increase to protect cells against toxic fatty acids generated through autophagy and provide fuel for beta-oxidation. However, the precise mechan...

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Detalles Bibliográficos
Autores principales: Hussain, Syed S., Tran, Tuyet-Minh, Ware, Timothy B., Luse, Melissa A., Prevost, Christopher T., Ferguson, Ashley N., Kashatus, Jennifer A., Hsu, Ku-Lung, Kashatus, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344381/
https://www.ncbi.nlm.nih.gov/pubmed/34320341
http://dx.doi.org/10.1016/j.celrep.2021.109451