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Placental Expression of ACE2 and TMPRSS2 in Maternal Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Are Placental Defenses Mediated by Fetal Sex?

BACKGROUND: Expression of angiotensin-converting enzyme 2 (ACE2) and type II transmembrane serine protease (TMPRSS2), host molecules required for viral entry, may underlie sex differences in vulnerability to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated whet...

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Detalles Bibliográficos
Autores principales: Shook, Lydia L, Bordt, Evan A, Meinsohn, Marie-Charlotte, Pepin, David, De Guzman, Rose M, Brigida, Sara, Yockey, Laura J, James, Kaitlyn E, Sullivan, Mackenzie W, Bebell, Lisa M, Roberts, Drucilla J, Kaimal, Anjali J, Li, Jonathan Z, Schust, Danny, Gray, Kathryn J, Edlow, Andrea G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344531/
https://www.ncbi.nlm.nih.gov/pubmed/34293137
http://dx.doi.org/10.1093/infdis/jiab335