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Shorter Leukocyte Telomere Length Is Associated with Worse Survival of Patients with Bladder Cancer and Renal Cell Carcinoma

SIMPLE SUMMARY: Intrinsic telomere shortening promotes tumorigenesis in cells with impaired DNA damage repair mechanisms, as dysfunctional telomeres lead to chromosomal instability. More recent data show that the telomere length of peripheral blood leukocyte (PBL) cells can be a prognostic marker fo...

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Detalles Bibliográficos
Autores principales: Zheng, Xi, Wezel, Felix, Azoitei, Anca, Meessen, Sabine, Wang, Wenya, Najjar, Gregoire, Wang, Xue, Kraus, Johann M., Kestler, Hans A., John, Axel, Zengerling, Friedemann, Bolenz, Christian, Günes, Cagatay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345040/
https://www.ncbi.nlm.nih.gov/pubmed/34359672
http://dx.doi.org/10.3390/cancers13153774