Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells

SIMPLE SUMMARY: Cancer cells often show elevated replication stress and loss of cell cycle checkpoints. The ataxia telangiectasia and Rad3-related (ATR) and WEE1 kinases play roles in protecting cancer cells from high replication stress and in regulating the remaining cell cycle checkpoints. Inhibit...

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Detalles Bibliográficos
Autores principales: Rødland, Gro Elise, Hauge, Sissel, Hasvold, Grete, Bay, Lilli T. E., Raabe, Tine T. H., Joel, Mrinal, Syljuåsen, Randi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345075/
https://www.ncbi.nlm.nih.gov/pubmed/34359691
http://dx.doi.org/10.3390/cancers13153790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345075/
https://www.ncbi.nlm.nih.gov/pubmed/34359691
http://dx.doi.org/10.3390/cancers13153790

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