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Human Wnt/β-Catenin Regulates Alloimmune Signaling during Allogeneic Transplantation

SIMPLE SUMMARY: This manuscript showed that Wnt/β-catenin plays a significant role in T cell-mediated GVHD after allogeneic transplantation. Our functional and genetic data demonstrated that the Wnt/β-catenin pathways play a central role in uncoupling GVHD from GVL functions. ABSTRACT: Allogeneic he...

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Detalles Bibliográficos
Autores principales: Mammadli, Mahinbanu, Harris, Rebecca, Mahmudlu, Sara, Verma, Anjali, May, Adriana, Dhawan, Rohan, Waickman, Adam T., Sen, Jyoti Misra, August, Avery, Karimi, Mobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345079/
https://www.ncbi.nlm.nih.gov/pubmed/34359702
http://dx.doi.org/10.3390/cancers13153798