Cargando…
Human Wnt/β-Catenin Regulates Alloimmune Signaling during Allogeneic Transplantation
SIMPLE SUMMARY: This manuscript showed that Wnt/β-catenin plays a significant role in T cell-mediated GVHD after allogeneic transplantation. Our functional and genetic data demonstrated that the Wnt/β-catenin pathways play a central role in uncoupling GVHD from GVL functions. ABSTRACT: Allogeneic he...
Autores principales: | Mammadli, Mahinbanu, Harris, Rebecca, Mahmudlu, Sara, Verma, Anjali, May, Adriana, Dhawan, Rohan, Waickman, Adam T., Sen, Jyoti Misra, August, Avery, Karimi, Mobin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345079/ https://www.ncbi.nlm.nih.gov/pubmed/34359702 http://dx.doi.org/10.3390/cancers13153798 |
Ejemplares similares
-
TCF-1 Is Required for CD4 T Cell Persistence Functions during AlloImmunity
por: Mammadli, Mahinbanu, et al.
Publicado: (2023) -
Interleukin‐2‐inducible T‐cell kinase (Itk) signaling regulates potent noncanonical regulatory T cells
por: Mammadli, Mahinbanu, et al.
Publicado: (2021) -
Targeting SLP76:ITK interaction separates GVHD from GVL in allo-HSCT
por: Mammadli, Mahinbanu, et al.
Publicado: (2021) -
TCF-1 regulates NKG2D expression on CD8 T cells during anti-tumor responses
por: Harris, Rebecca, et al.
Publicado: (2022) -
CrkL is required for donor T cell migration to GvHD target organs
por: Roy, Nathan H., et al.
Publicado: (2020)