Functional Analysis of Non-Genetic Resistance to Platinum in Epithelial Ovarian Cancer Reveals a Role for the MBD3-NuRD Complex in Resistance Development

SIMPLE SUMMARY: Most epithelial ovarian cancer (EOC) patients, although initially responsive to standard treatment with platinum-based chemotherapy, develop platinum resistance over the clinical course and succumb due to drug-resistant metastases. It has long been hypothesized that resistance to pla...

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Detalles Bibliográficos
Autores principales: Bauer, Tabea L., Collmar, Katrin, Kaltofen, Till, Loeffler, Ann-Katrin, Decker, Lorena, Mueller, Jan, Pinter, Sabine, Eisler, Stephan A., Mahner, Sven, Fraungruber, Patricia, Kommoss, Stefan, Staebler, Annette, Francis, Lewis, Conlan, R. Steven, Zuber, Johannes, Jeschke, Udo, Trillsch, Fabian, Rathert, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345099/
https://www.ncbi.nlm.nih.gov/pubmed/34359703
http://dx.doi.org/10.3390/cancers13153801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345099/
https://www.ncbi.nlm.nih.gov/pubmed/34359703
http://dx.doi.org/10.3390/cancers13153801

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