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Geospatial Assessments of DNA Adducts in the Human Stomach: A Model of Field Cancerization

SIMPLE SUMMARY: The geospatial distribution of DNA adducts, the presumable origins of mutations causing human cancers in the stomach was described. In human stomach resections for gastric cancer, seven different DNA adducts, C5-methyl-2′-deoxycytidine, 2′-deoxyinosine, C5-hydroxymethyl-2′-deoxycytid...

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Detalles Bibliográficos
Autores principales: Iwashita, Yuji, Ohnishi, Ippei, Matsushita, Yuto, Ohtsuka, Shunsuke, Yamashita, Takashi, Inaba, Keisuke, Fukazawa, Atsuko, Ochiai, Hideto, Matsumoto, Keigo, Kurono, Nobuhito, Matsushima, Yoshitaka, Mori, Hiroki, Suzuki, Shioto, Suzuki, Shohachi, Tanioka, Fumihiko, Sugimura, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345122/
https://www.ncbi.nlm.nih.gov/pubmed/34359626
http://dx.doi.org/10.3390/cancers13153728