Selective Inhibition of Aurora Kinase A by AK-01/LY3295668 Attenuates MCC Tumor Growth by Inducing MCC Cell Cycle Arrest and Apoptosis

SIMPLE SUMMARY: Merkel cell carcinoma is a deadly skin cancer with few treatment options. When the tumor has spread, less than 18% of patients survive past five years, and the mortality rate is 3-times higher than melanoma. Cancer immunotherapy is a promising field, harnessing the patient’s immune s...

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Detalles Bibliográficos
Autores principales: Das, Bhaba K., Kannan, Aarthi, Nguyen, Quy, Gogoi, Jyoti, Zhao, Haibo, Gao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345130/
https://www.ncbi.nlm.nih.gov/pubmed/34359608
http://dx.doi.org/10.3390/cancers13153708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345130/
https://www.ncbi.nlm.nih.gov/pubmed/34359608
http://dx.doi.org/10.3390/cancers13153708

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