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Cloud Computing Based Immunopeptidomics Utilizing Community Curated Variant Libraries Simplifies and Improves Neo-Antigen Discovery in Metastatic Melanoma

SIMPLE SUMMARY: Peptides expressed on the cell surface can be used to distinguish between diseased and healthy cells and for precision drug targeting. Ideal targets in cancer diagnostics and therapeutic development are the result of altered peptide sequences that make it to the surface as expressed...

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Detalles Bibliográficos
Autores principales: Prakash, Amol, Mahoney, Keira E., Orsburn, Benjamin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345142/
https://www.ncbi.nlm.nih.gov/pubmed/34359654
http://dx.doi.org/10.3390/cancers13153754