BRCA2 Promotes Spontaneous Homologous Recombination In Vivo

SIMPLE SUMMARY: Inherited mutation of either BRCA1 or BRCA2 is associated with familial breast and ovarian cancer. As a tumor suppressor, BRCA2 functions to maintain genome stability but we do not know the genomic impact of this deficiency on normal tissues in normal contexts, rather than cancer cel...

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Detalles Bibliográficos
Autores principales: Brown, Adam D., Greenman, Scott, Claybon, Alison B., Bishop, Alexander J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345144/
https://www.ncbi.nlm.nih.gov/pubmed/34359565
http://dx.doi.org/10.3390/cancers13153663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345144/
https://www.ncbi.nlm.nih.gov/pubmed/34359565
http://dx.doi.org/10.3390/cancers13153663

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