Targeting BRF2 in Cancer Using Repurposed Drugs

SIMPLE SUMMARY: BRF2, a subunit of the RNA polymerase III transcription complex, is upregulated in a wide variety of cancers and is a potential therapeutic target; however, no effective drugs are available to target BRF2. The upregulation of BRF2 in cancer cells confers survival via the prevention o...

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Detalles Bibliográficos
Autores principales: Rashidieh, Behnam, Molakarimi, Maryam, Mohseni, Ammar, Tria, Simon Manuel, Truong, Hein, Srihari, Sriganesh, Adams, Rachael C., Jones, Mathew, Duijf, Pascal H. G., Kalimutho, Murugan, Khanna, Kum Kum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345145/
https://www.ncbi.nlm.nih.gov/pubmed/34359683
http://dx.doi.org/10.3390/cancers13153778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345145/
https://www.ncbi.nlm.nih.gov/pubmed/34359683
http://dx.doi.org/10.3390/cancers13153778

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