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Follicular Helper T Cells Remodel the Immune Microenvironment of Pancreatic Cancer via Secreting CXCL13 and IL-21

SIMPLE SUMMARY: The immunosuppressive microenvironment is closely related to the poor prognosis of patients with PDAC. Tfh cells play an anti-tumor function in various malignant solid tumors; however, the role of Tfh cells in PDAC has not been determined. In this study, we aimed to explore the funct...

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Detalles Bibliográficos
Autores principales: Lin, Xuan, Ye, Longyun, Wang, Xu, Liao, Zhenyu, Dong, Jia, Yang, Ying, Zhang, Rulin, Li, Hao, Li, Pengcheng, Ding, Lei, Li, Tianjiao, Zhang, Wuhu, Xu, Shuaishuai, Han, Xuan, Xu, Huaxiang, Wang, Wenquan, Gao, Heli, Yu, Xianjun, Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345153/
https://www.ncbi.nlm.nih.gov/pubmed/34359579
http://dx.doi.org/10.3390/cancers13153678