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Proteins from the DNA Damage Response: Regulation, Dysfunction, and Anticancer Strategies
SIMPLE SUMMARY: Cells respond to genotoxic stress through complex protein pathways called DNA damage response (DDR). These mechanisms ensure the preservation of genomic integrity and activate DNA repair, cell cycle regulation, and, ultimately, programmed cell death. When altered, the DDR protein net...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345162/ https://www.ncbi.nlm.nih.gov/pubmed/34359720 http://dx.doi.org/10.3390/cancers13153819 |