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Repurposing Ferumoxytol as a Breast Cancer-Associated Macrophage Tracer with Five-Dimensional Quantitative [Fe]MRI of SPION Dynamics

SIMPLE SUMMARY: With the incorporation of immune-modulating therapies into the standard management of triple-negative breast cancer, there is increased interest in the non-invasive imaging of the tumor immune microenvironment. Ferumoxytol is FDA-approved as an iron replacement therapy for iron-defic...

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Detalles Bibliográficos
Autores principales: Sillerud, Laurel O., Neuwelt, Alexander J., Staquicini, Fernanda I., Arap, Wadih, Pasqualini, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345165/
https://www.ncbi.nlm.nih.gov/pubmed/34359704
http://dx.doi.org/10.3390/cancers13153802