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Therapeutic Potential of EWSR1–FLI1 Inactivation by CRISPR/Cas9 in Ewing Sarcoma

SIMPLE SUMMARY: Ewing sarcoma is an aggressive tumor with still unacceptable survival rates, particularly in patients with metastatic disease and for which it is necessary to develop new and innovative therapies. These tumors are characterized by the presence of chromosomal translocations that give...

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Detalles Bibliográficos
Autores principales: Cervera, Saint T., Rodríguez-Martín, Carlos, Fernández-Tabanera, Enrique, Melero-Fernández de Mera, Raquel M., Morin, Matias, Fernández-Peñalver, Sergio, Iranzo-Martínez, Maria, Amhih-Cardenas, Jorge, García-García, Laura, González-González, Laura, Moreno-Pelayo, Miguel Angel, Alonso, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345183/
https://www.ncbi.nlm.nih.gov/pubmed/34359682
http://dx.doi.org/10.3390/cancers13153783