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Collapse of Intra-Tumor Cooperation Induced by Engineered Defector Cells

SIMPLE SUMMARY: Using experiments in vitro and a mathematical model, I show that genetically modified cancer cells in which the gene for an essential growth factor is knocked out can spread in a population of cells that produce that growth factor, leading to an overall reduction in proliferation—a p...

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Detalles Bibliográficos
Autor principal: Archetti, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345189/
https://www.ncbi.nlm.nih.gov/pubmed/34359576
http://dx.doi.org/10.3390/cancers13153674