Geospatial Cellular Distribution of Cancer-Associated Fibroblasts Significantly Impacts Clinical Outcomes in Metastatic Clear Cell Renal Cell Carcinoma

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) are highly prevalent cells in the clear cell renal cell carcinoma (ccRCC) tumor immune microenvironment. CAFs are thought to potentiate tumor proliferation primarily through paracrine interactions, as evidenced by laboratory-based studies. We soug...

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Detalles Bibliográficos
Autores principales: Chakiryan, Nicholas H., Kimmel, Gregory J., Kim, Youngchul, Johnson, Joseph O., Clark, Noel, Hajiran, Ali, Chang, Andrew, Aydin, Ahmet M., Zemp, Logan, Katende, Esther, Chahoud, Jad, Ferrall-Fairbanks, Meghan C., Spiess, Philippe E., Francis, Natasha, Fournier, Michelle, Dhillon, Jasreman, Park, Jong Y., Wang, Liang, Mulé, James J., Altrock, Philipp M., Manley, Brandon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345222/
https://www.ncbi.nlm.nih.gov/pubmed/34359645
http://dx.doi.org/10.3390/cancers13153743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345222/
https://www.ncbi.nlm.nih.gov/pubmed/34359645
http://dx.doi.org/10.3390/cancers13153743

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