Intermittent Hypoxia Mediates Paraspeckle Protein-1 Upregulation in Sleep Apnea

SIMPLE SUMMARY: Patients with obstructive sleep apnea (OSA) exhibit an intermittent hypoxia-dependent paraspeckle protein-1 (PSPC1) increase, which is eventually delivered to the plasma through its cleavage from OSA monocytes by matrix metalloprotease-2, promoting tumor growth factor (TGFβ) expressi...

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Detalles Bibliográficos
Autores principales: Díaz-García, Elena, García-Tovar, Sara, Casitas, Raquel, Jaureguizar, Ana, Zamarrón, Ester, Sánchez-Sánchez, Begoña, Sastre-Perona, Ana, López-Collazo, Eduardo, Garcia-Rio, Francisco, Cubillos-Zapata, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345391/
https://www.ncbi.nlm.nih.gov/pubmed/34359789
http://dx.doi.org/10.3390/cancers13153888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345391/
https://www.ncbi.nlm.nih.gov/pubmed/34359789
http://dx.doi.org/10.3390/cancers13153888

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