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The Present State of Lithium for the Prevention of Dementia Related to Alzheimer’s Dementia in Clinical and Epidemiological Studies: A Critical Review

Despite the unavailability of essential anti-dementia drugs, lithium may inhibit glycogen synthase kinase-3 (GSK-3) and decrease beta-amyloid and hyper-phosphorylated tau. In this review, we hypothesized that trace to standard levels of lithium (i.e., corresponding to the therapeutic levels for bipo...

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Detalles Bibliográficos
Autores principales: Ishii, Nobuyoshi, Terao, Takeshi, Hirakawa, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345730/
https://www.ncbi.nlm.nih.gov/pubmed/34360049
http://dx.doi.org/10.3390/ijerph18157756