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The Most Common VHL Point Mutation R167Q in Hereditary VHL Disease Interferes with Cell Plasticity Regulation

SIMPLE SUMMARY: Von Hippel–Lindau (VHL) disease is characterized by mutations in the VHL gene, which can induce numerous benign and malignant tumors in different organs, as well as highly vascularized clear cell renal cell carcinomas (ccRCCs). The aim of this study was to examine whether the VHL-R16...

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Detalles Bibliográficos
Autores principales: Buart, Stéphanie, Terry, Stéphane, Diop, M’boyba Khadija, Dessen, Philippe, Couvé, Sophie, Abdou, Abdérémane, Adam, Julien, Thiery, Jérôme, Savagner, Pierre, Chouaib, Salem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345752/
https://www.ncbi.nlm.nih.gov/pubmed/34359798
http://dx.doi.org/10.3390/cancers13153897