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Emergence of directional bias in tau deposition from axonal transport dynamics

Defects in axonal transport may partly underpin the differences between the observed pathophysiology of Alzheimer’s disease (AD) and that of other non-amyloidogenic tauopathies. Particularly, pathological tau variants may have molecular properties that dysregulate motor proteins responsible for the...

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Detalles Bibliográficos
Autores principales: Torok, Justin, Maia, Pedro D., Verma, Parul, Mezias, Christopher, Raj, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345857/
https://www.ncbi.nlm.nih.gov/pubmed/34314441
http://dx.doi.org/10.1371/journal.pcbi.1009258