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New Insights into Cancer Targeted Therapy: Nodal and Cripto-1 as Attractive Candidates

The transforming growth factor beta (TGF-β) signaling is fundamental for correct embryonic development. However, alterations of this pathway have been correlated with oncogenesis, tumor progression and sustaining of cancer stem cells (CSCs). Cripto-1 (CR-1) and Nodal are two embryonic proteins invol...

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Detalles Bibliográficos
Autores principales: Arboretto, Paola, Cillo, Michele, Leonardi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345935/
https://www.ncbi.nlm.nih.gov/pubmed/34360603
http://dx.doi.org/10.3390/ijms22157838