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Novel N-Substituted Amino Acid Hydrazone-Isatin Derivatives: Synthesis, Antioxidant Activity, and Anticancer Activity in 2D and 3D Models In Vitro

A series of novel mono and bishydrazones each bearing a 2-oxindole moiety along with substituted phenylaminopropanamide, pyrrolidin-2-one, benzimidazole, diphenylmethane, or diphenylamine fragments were synthesized, and their anticancer activities were tested by MTT assay against human melanoma A375...

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Detalles Bibliográficos
Autores principales: Tumosienė, Ingrida, Jonuškienė, Ilona, Kantminienė, Kristina, Mickevičius, Vytautas, Petrikaitė, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346030/
https://www.ncbi.nlm.nih.gov/pubmed/34360565
http://dx.doi.org/10.3390/ijms22157799