Selective Chemical Activation of Piezo1 in Leukemia Cell Membrane: Single Channel Analysis

Piezo1/2 are mechanosensitive calcium-permeable channels that can be activated by various modes of membrane deformation. The identification of the small molecule Yoda1, a synthetic Piezo1 agonist, revealed the possibility of chemical activation of the channel. Stimulating effects of Yoda1 on Piezo1...

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Detalles Bibliográficos
Autores principales: Vasileva, Valeria, Morachevskaya, Elena, Sudarikova, Anastasia, Negulyaev, Yuri, Chubinskiy-Nadezhdin, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346046/
https://www.ncbi.nlm.nih.gov/pubmed/34360605
http://dx.doi.org/10.3390/ijms22157839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346046/
https://www.ncbi.nlm.nih.gov/pubmed/34360605
http://dx.doi.org/10.3390/ijms22157839

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