Losartan Prevents Hepatic Steatosis and Macrophage Polarization by Inhibiting HIF-1α in a Murine Model of NAFLD

Hypoxia and hepatosteatosis microenvironments are fundamental traits of nonalcoholic fatty liver disease (NAFLD). Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that controls the cellular response to hypoxia and is activated in hepatocytes of patients with NAFLD, whereas the route an...

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Detalles Bibliográficos
Autores principales: Wang, Cheng-Hui, Liu, Hsuan-Miao, Chang, Zi-Yu, Huang, Tse-Hung, Lee, Tzung-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346090/
https://www.ncbi.nlm.nih.gov/pubmed/34360607
http://dx.doi.org/10.3390/ijms22157841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346090/
https://www.ncbi.nlm.nih.gov/pubmed/34360607
http://dx.doi.org/10.3390/ijms22157841

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