Cargando…
Losartan Prevents Hepatic Steatosis and Macrophage Polarization by Inhibiting HIF-1α in a Murine Model of NAFLD
Hypoxia and hepatosteatosis microenvironments are fundamental traits of nonalcoholic fatty liver disease (NAFLD). Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that controls the cellular response to hypoxia and is activated in hepatocytes of patients with NAFLD, whereas the route an...
Autores principales: | Wang, Cheng-Hui, Liu, Hsuan-Miao, Chang, Zi-Yu, Huang, Tse-Hung, Lee, Tzung-Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346090/ https://www.ncbi.nlm.nih.gov/pubmed/34360607 http://dx.doi.org/10.3390/ijms22157841 |
Ejemplares similares
-
Losartan Attenuates Insulin Resistance and Regulates Browning Phenomenon of White Adipose Tissue in ob/ob Mice
por: Liu, Hsuan-Miao, et al.
Publicado: (2021) -
Randomized placebo‐controlled trial of losartan for pediatric NAFLD
por: Vos, Miriam B., et al.
Publicado: (2022) -
Effects of losartan in patients with NAFLD: A meta-analysis of randomized controlled trial
por: Meng, Chang, et al.
Publicado: (2023) -
Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD
por: Gonzalez, Concepcion, et al.
Publicado: (2013) -
Parenteral Nutrition Associated Hepatic Steatosis and NAFLD Intersect at AMPK
por: Guthrie, Gregory
Publicado: (2022)