Single Nucleotide Polymorphism Induces Divergent Dynamic Patterns in CYP3A5: A Microsecond Scale Biomolecular Simulation of Variants Identified in Sub-Saharan African Populations

Pharmacogenomics aims to reveal variants associated with drug response phenotypes. Genes whose roles involve the absorption, distribution, metabolism, and excretion of drugs, are highly polymorphic between populations. High coverage whole genome sequencing showed that a large proportion of the varia...

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Detalles Bibliográficos
Autores principales: Othman, Houcemeddine, da Rocha, Jorge E. B., Hazelhurst, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346100/
https://www.ncbi.nlm.nih.gov/pubmed/34360551
http://dx.doi.org/10.3390/ijms22157786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346100/
https://www.ncbi.nlm.nih.gov/pubmed/34360551
http://dx.doi.org/10.3390/ijms22157786

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