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Mitochondrial Dysfunction and Alterations in Mitochondrial Permeability Transition Pore (mPTP) Contribute to Apoptosis Resistance in Idiopathic Pulmonary Fibrosis Fibroblasts

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by increased activation of fibroblasts/myofibroblasts. Previous reports have shown that IPF fibroblasts are resistant to apoptosis, but the mechanisms remain unclear. Since inhibition of the mitochondrial permeability transit...

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Detalles Bibliográficos
Autores principales: Luis-García, Erika Rubí, Becerril, Carina, Salgado-Aguayo, Alfonso, Aparicio-Trejo, Omar Emiliano, Romero, Yair, Flores-Soto, Edgar, Mendoza-Milla, Criselda, Montaño, Martha, Chagoya, Victoria, Pedraza-Chaverri, José, El Hafidi, Mohammed, Orozco-Ibarra, Marisol, Pardo, Annie, Selman, Moisés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346102/
https://www.ncbi.nlm.nih.gov/pubmed/34360637
http://dx.doi.org/10.3390/ijms22157870