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Mitochondrial Dysfunction and Alterations in Mitochondrial Permeability Transition Pore (mPTP) Contribute to Apoptosis Resistance in Idiopathic Pulmonary Fibrosis Fibroblasts
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by increased activation of fibroblasts/myofibroblasts. Previous reports have shown that IPF fibroblasts are resistant to apoptosis, but the mechanisms remain unclear. Since inhibition of the mitochondrial permeability transit...
Autores principales: | Luis-García, Erika Rubí, Becerril, Carina, Salgado-Aguayo, Alfonso, Aparicio-Trejo, Omar Emiliano, Romero, Yair, Flores-Soto, Edgar, Mendoza-Milla, Criselda, Montaño, Martha, Chagoya, Victoria, Pedraza-Chaverri, José, El Hafidi, Mohammed, Orozco-Ibarra, Marisol, Pardo, Annie, Selman, Moisés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346102/ https://www.ncbi.nlm.nih.gov/pubmed/34360637 http://dx.doi.org/10.3390/ijms22157870 |
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