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Synthesis of New Tricyclic 1,2-Thiazine Derivatives with Anti-Inflammatory Activity

New, tricyclic compounds containing a sulfonyl moiety in their structure, as potential safer COX inhibitors, were designed and synthesized. New derivatives have three conjugated rings and a sulfonyl group. A third ring, i.e., an oxazine, oxazepine or oxazocin, has been added to the 1,2-benzothiazine...

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Detalles Bibliográficos
Autores principales: Maniewska, Jadwiga, Wiatrak, Benita, Czyżnikowska, Żaneta, Szczęśniak-Sięga, Berenika M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346139/
https://www.ncbi.nlm.nih.gov/pubmed/34360585
http://dx.doi.org/10.3390/ijms22157818