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Mechanistic Insights of Aberrant Splicing with Splicing Factor Mutations Found in Myelodysplastic Syndromes

Pre-mRNA splicing is an essential process for gene expression in higher eukaryotes, which requires a high order of accuracy. Mutations in splicing factors or regulatory elements in pre-mRNAs often result in many human diseases. Myelodysplastic syndrome (MDS) is a heterogeneous group of chronic myelo...

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Detalles Bibliográficos
Autores principales: Kataoka, Naoyuki, Matsumoto, Eri, Masaki, So
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346168/
https://www.ncbi.nlm.nih.gov/pubmed/34360561
http://dx.doi.org/10.3390/ijms22157789