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Investigating LMNA-Related Dilated Cardiomyopathy Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

LMNA-related dilated cardiomyopathy is an inherited heart disease caused by mutations in the LMNA gene encoding for lamin A/C. The disease is characterized by left ventricular enlargement and impaired systolic function associated with conduction defects and ventricular arrhythmias. We hypothesized t...

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Detalles Bibliográficos
Autores principales: Shemer, Yuval, Mekies, Lucy N., Ben Jehuda, Ronen, Baskin, Polina, Shulman, Rita, Eisen, Binyamin, Regev, Danielle, Arbustini, Eloisa, Gerull, Brenda, Gherghiceanu, Mihaela, Gottlieb, Eyal, Arad, Michael, Binah, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346174/
https://www.ncbi.nlm.nih.gov/pubmed/34360639
http://dx.doi.org/10.3390/ijms22157874