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4-Phenylbutyric acid improves free fatty acid-induced hepatic insulin resistance in vivo

Plasma free fatty acids (FFAs) are elevated in obesity and can induce insulin resistance via endoplasmic reticulum (ER) stress. However, it is unknown whether hepatic insulin resistance caused by the elevation of plasma FFAs is alleviated by chemical chaperones. Rats received one of the following i....

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Detalles Bibliográficos
Autores principales: Pereira, Sandra, Moore, Jessy, Li, Jia-Xu, Yu, Wen Qin, Ghanim, Husam, Vlavcheski, Filip, Joseph, Yemisi Deborah, Dandona, Paresh, Volchuk, Allen, Cummins, Carolyn L, Tsiani, Evangelia, Giacca, Adria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346193/
https://www.ncbi.nlm.nih.gov/pubmed/34319253
http://dx.doi.org/10.1530/EC-21-0248