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Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis

Proper lung function relies on the precise balance of specialized epithelial cells that coordinate to maintain homeostasis. Herein, we describe essential roles for the transcriptional regulators YAP/TAZ in maintaining lung epithelial homeostasis, reporting that conditional deletion of Yap and Wwtr1/...

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Detalles Bibliográficos
Autores principales: Hicks-Berthet, Julia, Ning, Boting, Federico, Anthony, Tilston-Lunel, Andrew, Matschulat, Adeline, Ai, Xingbin, Lenburg, Marc E., Beane, Jennifer, Monti, Stefano, Varelas, Xaralabos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346236/
https://www.ncbi.nlm.nih.gov/pubmed/34260916
http://dx.doi.org/10.1016/j.celrep.2021.109347