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Discovery-stage identification of drug-like antibodies using emerging experimental and computational methods
There is intense and widespread interest in developing monoclonal antibodies as therapeutic agents to treat diverse human disorders. During early-stage antibody discovery, hundreds to thousands of lead candidates are identified, and those that lack optimal physical and chemical properties must be de...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346245/ https://www.ncbi.nlm.nih.gov/pubmed/34313532 http://dx.doi.org/10.1080/19420862.2021.1895540 |