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Discovery-stage identification of drug-like antibodies using emerging experimental and computational methods

There is intense and widespread interest in developing monoclonal antibodies as therapeutic agents to treat diverse human disorders. During early-stage antibody discovery, hundreds to thousands of lead candidates are identified, and those that lack optimal physical and chemical properties must be de...

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Detalles Bibliográficos
Autores principales: Makowski, Emily K., Wu, Lina, Gupta, Priyanka, Tessier, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346245/
https://www.ncbi.nlm.nih.gov/pubmed/34313532
http://dx.doi.org/10.1080/19420862.2021.1895540