Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study

The ability to investigate therapeutic interventions in animal models of neurodegenerative diseases depends on extensive characterization of the model(s) being used. There are numerous models that have been generated to study Alzheimer’s disease (AD) and the underlying pathogenesis of the disease. W...

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Detalles Bibliográficos
Autores principales: Oblak, Adrian L., Lin, Peter B., Kotredes, Kevin P., Pandey, Ravi S., Garceau, Dylan, Williams, Harriet M., Uyar, Asli, O’Rourke, Rita, O’Rourke, Sarah, Ingraham, Cynthia, Bednarczyk, Daria, Belanger, Melisa, Cope, Zackary A., Little, Gabriela J., Williams, Sean-Paul G., Ash, Carl, Bleckert, Adam, Ragan, Tim, Logsdon, Benjamin A., Mangravite, Lara M., Sukoff Rizzo, Stacey J., Territo, Paul R., Carter, Gregory W., Howell, Gareth R., Sasner, Michael, Lamb, Bruce T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346252/
https://www.ncbi.nlm.nih.gov/pubmed/34366832
http://dx.doi.org/10.3389/fnagi.2021.713726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346252/
https://www.ncbi.nlm.nih.gov/pubmed/34366832
http://dx.doi.org/10.3389/fnagi.2021.713726

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