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Genes Encoding Teleost Orthologs of Human Haploinsufficient and Monoallelically Expressed Genes Remain in Duplicate More Frequently Than the Whole Genome

Gene dosage is an important issue both in cell and evolutionary biology. Most genes are present in two copies or alleles in diploid eukariotic cells. The most outstanding exception is monoallelic gene expression (MA) that concerns genes localized on the X chromosome or in regions undergoing parental...

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Detalles Bibliográficos
Autores principales: Picolo, Floriane, Grandchamp, Anna, Piégu, Benoît, Rolland, Antoine D., Veitia, Reiner A., Monget, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346308/
https://www.ncbi.nlm.nih.gov/pubmed/34368340
http://dx.doi.org/10.1155/2021/9028667