A Phase I Clinical Trial to Assess Safety and Tolerability of Injectable Collagenase in Women with Symptomatic Uterine Fibroids

Uterine fibroids feature excessive deposition of types I and III collagen. Previous ex vivo studies showed an FDA-approved collagenase (EN3835)-digested types I and III collagen fibers in fibroid tissues; however, collagenase had not been evaluated in vivo for effects on uterine fibroids. The object...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Bhuchitra, Sims, Holly, Trueheart, Irene, Simpson, Khara, Wang, Karen C., Patzkowsky, Kristin, Wegman, Thomas, Soma, Jean-Marie, Dixon, Rosina, Jayes, Friederike, Voegltine, Kristin, Yenokyan, Gayane, Su, Szu-Chi, Leppert, Phyllis, Segars, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Fibroid: Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346429/
https://www.ncbi.nlm.nih.gov/pubmed/33914296
http://dx.doi.org/10.1007/s43032-021-00573-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346429/
https://www.ncbi.nlm.nih.gov/pubmed/33914296
http://dx.doi.org/10.1007/s43032-021-00573-8

Ejemplares similares