CryoEM reveals the stochastic nature of individual ATP binding events in a group II chaperonin

Chaperonins are homo- or hetero-oligomeric complexes that use ATP binding and hydrolysis to facilitate protein folding. ATP hydrolysis exhibits both positive and negative cooperativity. The mechanism by which chaperonins coordinate ATP utilization in their multiple subunits remains unclear. Here we...

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Detalles Bibliográficos
Autores principales: Zhao, Yanyan, Schmid, Michael F., Frydman, Judith, Chiu, Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346469/
https://www.ncbi.nlm.nih.gov/pubmed/34362932
http://dx.doi.org/10.1038/s41467-021-25099-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346469/
https://www.ncbi.nlm.nih.gov/pubmed/34362932
http://dx.doi.org/10.1038/s41467-021-25099-0

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