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Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice

Bariatric surgeries such as the Vertical Sleeve Gastrectomy (VSG) are invasive but provide the most effective improvements in obesity and Type 2 diabetes. We hypothesized a potential role for the gut hormone Fibroblast-Growth Factor 15/19 which is increased after VSG and pharmacologically can improv...

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Detalles Bibliográficos
Autores principales: Bozadjieva-Kramer, Nadejda, Shin, Jae Hoon, Shao, Yikai, Gutierrez-Aguilar, Ruth, Li, Ziru, Heppner, Kristy M., Chiang, Samuel, Vargo, Sara G., Granger, Katrina, Sandoval, Darleen A., MacDougald, Ormond A., Seeley, Randy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346483/
https://www.ncbi.nlm.nih.gov/pubmed/34362888
http://dx.doi.org/10.1038/s41467-021-24914-y