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Hypoxic stress suppresses lung tumor-secreted exosomal miR101 to activate macrophages and induce inflammation
Hypoxia promotes inflammation in the tumor microenvironment. Although hypoxia-inducible factor 1α (HIF1α) is a master modulator of the response to hypoxia, the exact mechanisms through which HIF1α regulates the induction of inflammation remain largely unclear. Using The Cancer Genome Atlas Lung Squa...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346509/ https://www.ncbi.nlm.nih.gov/pubmed/34362882 http://dx.doi.org/10.1038/s41419-021-04030-x |