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Interpretable deep recommender system model for prediction of kinase inhibitor efficacy across cancer cell lines

Computational models for drug sensitivity prediction have the potential to significantly improve personalized cancer medicine. Drug sensitivity assays, combined with profiling of cancer cell lines and drugs become increasingly available for training such models. Multiple methods were proposed for pr...

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Detalles Bibliográficos
Autores principales: Koras, Krzysztof, Kizling, Ewa, Juraeva, Dilafruz, Staub, Eike, Szczurek, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346627/
https://www.ncbi.nlm.nih.gov/pubmed/34362938
http://dx.doi.org/10.1038/s41598-021-94564-z