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Single paternal dexamethasone challenge programs offspring metabolism and reveals multiple candidates in RNA-mediated inheritance

Single traumatic events that elicit an exaggerated stress response can lead to the development of neuropsychiatric conditions. Rodent studies suggested germline RNA as a mediator of effects of chronic environmental exposures to the progeny. The effects of an acute paternal stress exposure on the ger...

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Detalles Bibliográficos
Autores principales: Gapp, Katharina, Parada, Guillermo E., Gross, Fridolin, Corcoba, Alberto, Kaur, Jasmine, Grau, Evelyn, Hemberg, Martin, Bohacek, Johannes, Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346661/
https://www.ncbi.nlm.nih.gov/pubmed/34386731
http://dx.doi.org/10.1016/j.isci.2021.102870