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Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases

BACKGROUND & AIMS: Sestrin 1/2/3 (Sesn1/2/3) belong to a small family of proteins that have been implicated in the regulation of metabolic homeostasis and oxidative stress. However, the underlying mechanisms remain incompletely understood. The aim of this work was to illustrate the collective fu...

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Detalles Bibliográficos
Autores principales: Fang, Zhigang, Kim, Hyeong-Geug, Huang, Menghao, Chowdhury, Kushan, Li, Ming O., Liangpunsakul, Suthat, Dong, X. Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346671/
https://www.ncbi.nlm.nih.gov/pubmed/33962074
http://dx.doi.org/10.1016/j.jcmgh.2021.04.015