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HD5 and LL-37 Inhibit SARS-CoV and SARS-CoV-2 Binding to Human ACE2 by Molecular Simulation

The coronavirus (COVID-19) pandemic is still spreading all over the world. As reported, angiotensin-converting enzyme-2 (ACE2) is a receptor of SARS-CoV-2 spike protein that initializes viral entry into host cells. Previously, the human defensin 5 (HD5) has been experimentally confirmed to be functi...

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Detalles Bibliográficos
Autores principales: Li, Daixi, Chen, Peiqin, Shi, Ting, Mehmood, Aamir, Qiu, Jingfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346780/
https://www.ncbi.nlm.nih.gov/pubmed/34363600
http://dx.doi.org/10.1007/s12539-021-00462-3