Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel

The heart pumps blood against the mechanical afterload from arterial resistance, and increased afterload may alter cardiac electrophysiology and contribute to life-threatening arrhythmias. However, the cellular and molecular mechanisms underlying mechanoelectric coupling in cardiomyocytes remain unc...

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Detalles Bibliográficos
Autores principales: Hegyi, Bence, Shimkunas, Rafael, Jian, Zhong, Izu, Leighton T., Bers, Donald M., Chen-Izu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346795/
https://www.ncbi.nlm.nih.gov/pubmed/34326268
http://dx.doi.org/10.1073/pnas.2108484118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346795/
https://www.ncbi.nlm.nih.gov/pubmed/34326268
http://dx.doi.org/10.1073/pnas.2108484118

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