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Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons

There are sex differences in somatosensory sensitivity. Circulating estrogens appear to have a pronociceptive effect that explains why females are reported to be more sensitive to pain than males. Although itch symptoms develop during pregnancy in many women, the underlying mechanism of female-speci...

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Detalles Bibliográficos
Autores principales: Takanami, Keiko, Uta, Daisuke, Matsuda, Ken Ichi, Kawata, Mitsuhiro, Carstens, Earl, Sakamoto, Tatsuya, Sakamoto, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346901/
https://www.ncbi.nlm.nih.gov/pubmed/34312228
http://dx.doi.org/10.1073/pnas.2103536118