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Cholesterol Sequestration from Caveolae/Lipid Rafts Enhances Cationic Liposome-Mediated Nucleic Acid Delivery into Endothelial Cells

Delivering nucleic acids into the endothelium has great potential in treating vascular diseases. However, endothelial cells, which line the vasculature, are considered as sensitive in nature and hard to transfect. Low transfection efficacies in endothelial cells limit their potential therapeutic app...

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Detalles Bibliográficos
Autores principales: Maddila, Santhosh Chandar, Voshavar, Chandrashekhar, Arjunan, Porkizhi, Chowath, Rashmi Prakash, Rachamalla, Hari Krishna Reddy, Balakrishnan, Balaji, Balasubramanian, Poonkuzhali, Banerjee, Rajkumar, Marepally, Srujan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346983/
https://www.ncbi.nlm.nih.gov/pubmed/34361779
http://dx.doi.org/10.3390/molecules26154626